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3-FPM Powder

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3-Fluorophenmetrazine (also known as 3F-Phenmetrazine, PAL-593, and 3-FPM) is a novel stimulant substance of the phenylmorpholine class. 3-FPM is a derivative of phenmetrazine, a once-popular stimulant substance that was clinically used as an anorectic in Europe in the 1950s. It produces its activity by increasing the levels of serotonin, dopamine, and norepinephrine in the brain.


The synthesis and pharmacology of 3-FPM was first reported in a patent filed in 2011. Reports of human use first surfaced in early 2015 after it appeared for sale on the online research chemical market.

User reports indicate that 3-FPM produces classical stimulant effects comparable to those of amphetamine. Common effects include stimulation, enhanced focus and motivation, thought acceleration, and euphoria. Many reports describe 3-FPM as having a relatively subtle and controlled stimulant effect which produces less nervousness, insomnia and euphoria than other stimulants, which makes it suitable as a study-aid or productivity-enhancer.

Very little data exists about the pharmacological properties, metabolism, and toxicity of 3-FPM. Due to the lack of information on its properties, it is highly advised to use harm reduction practices if using this substance.

3-Fluorophenmetrazine (3-FPM) is a synthetic molecule of the amphetamine family. Molecules of the amphetamine class contain a phenethylamine core featuring a phenyl ring bound to an amino (NH2) group through an ethyl chain with an additional methyl substitution at Rα. Amphetamines are alpha-methylated phenethylamines. 3-FPM contains a fluorine atom attached at R3 of the phenyl ring. Additionally, part of its amphetamine skeleton is incorporated into a morpholine ring. At R2 of its chain, an oxygen group is bound -- this oxygen group is linked by an ethyl chain to the terminal amine of the amphetamine chain to form a morpholine group. 3-FPM is a fluorinated derivative of phenmetrazine.

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Other names

3FPM

CAS Number

1350768-28-3

IUPAC Name

2-(3-fluorophenyl)-3-methylmorpholine

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